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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
Descriptors Found:
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DeCS
Descriptor
English
:
Cystic Fibrosis Transmembrane Conductance Regulator
Descriptor
Spanish
:
regulador de la conductancia transmembrana de la fibrosis quística
Descriptor
Portuguese
:
Regulador de Condutância Transmembrana em Fibrose Cística
Synonyms
English
:
CFTR Protein
Chloride channels, ATP gated CFTR
Chloride channels, ATP-gated CFTR
Protein, CFTR
Tree Number:
D12.776.157.530.100.304.500
D12.776.157.530.400.175.125
D12.776.157.530.450.074.500.500.500.500
D12.776.543.550.450.175.125
D12.776.543.585.100.304.500
D12.776.543.585.400.175.125
D12.776.543.585.450.074.500.500.500.500
Definition
English
:
A chloride channel that regulates secretion in many exocrine
tissues
. Abnormalities in the CFTR gene have been shown to cause
cystic fibrosis
. (Hum Genet 1994;93(4):364-8)
History Note
English
:
96; was CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (NM) 1989-95
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
32784
Unique Identifier:
D019005
Occurrence in VHL
:
Similar:
DeCS